Deals
Neurocrine Pays $2.9B for Soleno's Prader-Willi Drug
Neurocrine pays $53/share in cash for Soleno Therapeutics, acquiring Vykat XR, a profitable approved treatment for Prader-Willi syndrome.
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Deals
Gilead Cuts 51 Foster City Jobs One Year After Same Layoff
Gilead cuts 51 Foster City jobs effective May 29, one year after the same HQ shed 149. The backdrop: ~$10B in acquisitions closed since February.
FDA
Lipocine's PPD Drug Fails Phase 3, Stock Craters 77%
Lipocine's oral brexanolone failed Phase 3 for postpartum depression, wiping 77% off its stock. The pill version of Zulresso didn't work.
FDA
Novo Fires Back at Lilly's Foundayo With Competing Efficacy Data
Novo Nordisk published rival efficacy data the day after FDA approved Lilly's oral obesity pill Foundayo — but no head-to-head trial exists to back the claims.
FDA
Pfizer Scraps COVID Vaccine Trial; 80% of Recruits Failed Screening
Pfizer and BioNTech shut down their 25,000–30,000-person COVID trial after 80%+ of recruits failed screening, leaving FDA-required approval data ungenerated.
FDA
White House Asks for $15.8B HHS Cut — Congress Already Said No Once
White House requests $15.8B HHS cut for FY2027, including a $5B NIH reduction and three institute eliminations. Congress rejected a bigger ask last year.
Deals
Syneron Bio Pulls $150M Series B Four Months After $100M Round
Syneron Bio raises $150M Series B, bringing total funding to $250M in four months, backed by AstraZeneca and Abu Dhabi sovereign wealth.
Deals
OpenEvidence Buys Tandem to Automate Prior Authorization
OpenEvidence acquires Tandem to add AI-driven prior authorization to its doctor-facing platform, threatening standalone PA automation vendors.
Deals
Lilly Pays $115M Upfront in Insilico AI Deal Worth Up to $2.75B
Eli Lilly paid $115M upfront for an AI collaboration with Insilico Medicine worth up to $2.75B, with milestone math that heavily favors Lilly.
Legal
DOJ Backs Pharma on 340B, Leaving Safety-Net Hospitals Exposed
The DOJ reversed course to back pharma in the 340B contract pharmacy dispute, leaving safety-net hospitals without a federal ally.
Legal
Trump Signs 100% Tariff Order on Imported Drugs
Trump signed an executive order imposing 100% tariffs on drug imports from countries without U.S. trade deals, effective within months.
Deals
Blackstone Raises New Fund as Two Pharma Giants Close March Megadeals
Two pharma giants closed megadeals in March while Blackstone raised a new fund — more dry powder chasing the same targets means multiples only go one way.
Deals
Biogen Drops $5.6B for Apellis at 140% Premium, Shares Fall
Biogen acquires Apellis for $5.6B at a near 140% premium, adding Syfovre and Empaveli to offset a fading MS franchise ahead of pharma's patent cliff.
FDA
FDA Clears Novocure's Pancreatic Cancer Device in First-Ever Approval
FDA approved Novocure's Optune Pax for locally advanced pancreatic cancer, the first device cleared for it, adding ~2 months to survival over standard chemo.
FDA
FDA Clears 7.2mg Wegovy HD for Novo Nordisk in 54-Day Sprint
FDA cleared Novo Nordisk's 7.2mg Wegovy HD in 54 days under its national priority program, pushing the GLP-1's efficacy ceiling higher.
fda