Bought PolyPeptide for $1.8B in Samsung's Peptide Push
Samsung Biologics pays just a 6% premium for PolyPeptide, its second buyout in eight months and Korea's largest-ever biopharma deal.
Masthead · Deals & M&A Writer
San Francisco · Joined January 2026
Ex-Morgan Stanley healthcare banker. Tracks every pharma deal over $50M. Last year: 180+ deals, $290B combined. San Francisco.
Samsung Biologics pays just a 6% premium for PolyPeptide, its second buyout in eight months and Korea's largest-ever biopharma deal.
BlossomHill is asking public markets for $100M to challenge AstraZeneca's $7.25B-a-year Tagrisso, backed by nothing past phase 1/2 data.
Comerica's board took a 20% premium in October. Now Fifth Third's $850 million synergy bet gets tested over the Labor Day weekend conversion.
Lakestar closed a $300 million fund betting Brussels' sovereignty anxiety turns into procurement revenue for Helsing and Auterion.
Gilead paid $7.8B for Arcellx's CAR-T pipeline, then eliminated 192 of its 220 employees, 87% of the entire staff, within weeks of closing.
First Bank is paying $166 million for a privately held SC lender with no public price to set a premium. It adds $831M in assets and 14 branches.
Attovia wants public money for a drug that hasn't started phase 2, betting it can unseat a franchise Galderma just repriced to $4B.
First Hawaiian is paying $63.12 a share in stock for TriCo, its second attempt at a mainland network since losing one to BMO in 2023.
Spero can't match AbbVie's $10.9B checkbook, so it mortgaged an FDA-approved antibiotic's royalties to fund a $1.1B autoimmune bet instead.
AstraZeneca pays $1.5B for Dizal's Zegfrovy, skips the Greater China carve-out, and bets on frontline data it hasn't won approval for yet.
Apnimed banked $100M from Shionogi in March, then filed a blank-check IPO to fund its sleep apnea pill still awaiting an FDA verdict.
OpenAI won't replace Fidji Simo. Greg Brockman just inherited her job, her budget line, and the products that actually make OpenAI money.
Nu spent six years chasing a Mexican bank charter, nine months behind Revolut. The 30-day countdown to full bank status starts now.
Oregon says Paramount is racing to close its $110B Warner Bros. Discovery buy before regulators can finish digging through the records.
A 31-23 party-line vote pushes a federal EWA framework to the House floor, stripping states of power to call these wage advances loans.
Altimeter, D1 and SoftBank just wrote the first outside check to Josh Kushner's AI roll-up vehicle. No price or premium was disclosed.
SK Hynix's $29 billion Nasdaq bid would top Alibaba's 2014 IPO record, betting Wall Street pays more for AI exposure than Seoul does.
Novartis just paid $1.1B for a biotech whose lead drugs have never touched a human patient. The math on that bet doesn't look cheap.
Starling axed 130 jobs right after profits fell and a £29 million FCA fine for "shockingly lax" crime controls still weighs on the ledger.
AstraZeneca puts just $30M down now to control up to $1.77B in kidney-drug milestones, its fourth check written to Chinese partner CSPC since 2024.
Kraken's parent paid up to $600M for a Hong Kong payments firm — here's what Payward actually bought, and why the discount to Stripe's Bridge deal.
No share price, no premium to measure. Just a binary bet: $227M upfront now, up to $796M if potravitug clears its kidney-transplant trial.
A federal lending program built to rescue small businesses now owes taxpayers an answer: why is a third of its $16.6B book underwater?
Atom Bank's £600M auction couldn't find a full-price buyer, and shareholders are now weighing whether management should pay the price.
Elroy Air's cargo drone, built to replace trucks on middle-mile routes, could hit public markets by Friday via a $1B SPAC with Columbus Circle.
World Leaks posted 200,000 files from Tata's breach, including Apple iPhone schematics and PCB designs. Dell and Nike were the warm-up.
Walmart's undisclosed Vibe.co deal plugs the SMB gap in its CTV stack, coming one day after it unified ad ops across Walmart Connect and Sam's Club.
Lilly converts a $1.4B milestone obligation into a $50M clean platform buy; Sangamo's Chapter 11 shows how bankruptcy reshapes deal math.
Nuvectis paid $40M upfront for ex-China rights to Haisco's once-daily Factor B inhibitor in a PNH market projected above $5B in 2026.
SK Biopharmaceuticals is putting $18M upfront on a $2.5B Insilico neuroimmune deal — and the backloaded structure tells you who blinked.
Kalshi hit $2B in annualized revenue, doubled its valuation in five months, and is now talking to banks about an IPO it won't need until 2027.
Memento raised $93M and licensed a VEGF-Tie2 bispecific for nAMD and DME, conditions driving $4.4B in U.S. Eylea franchise sales last year.
A dormant API credential let Icarus harvest OAuth tokens from Klue, taking CRM data from Huntress and prompting Salesforce to pull the plug.
Icarus extortion group turned a dormant Klue API credential into a Salesforce pivot hitting Recorded Future, Huntress, and five more firms.
Accenture paid roughly 20x ARR for Dragos, runZero, and NetRise, betting AI threats will turn a $27B OT security market into $59B by 2031.
Santander's $12.3B Webster bid cleared OCC in 74 days, but Fed, ECB, and DOJ reviews still stand between Santander and a $327B U.S. lender.
Santander's $12.2B Webster deal cleared the OCC, but the Federal Reserve and ECB still hold the pen on a close worth $75 per share.
Jazz dropped $56M to option into AbCellera's T cell engager pipeline for GI cancer, days after Zepzelca's Phase 3 failed its SCLC expansion.
SpaceX's $60B Cursor deal prices the startup at 23x revenue. Days after the IPO. The catch: Anthropic already controls half the AI coding market.
DOJ greenlit a $111B streaming merger over the objections of its own antitrust staff, and state AGs are already lining up a lawsuit to stop it.
Salesforce's $3.6B buy of Fin prices its Apex model at nine times ARR, an 80% premium to the company's last reported secondary valuation.
Fox agreed to pay $160 a share for Roku, a $22B bet that owning the streaming distribution pipe is worth more than just filling it with content.
Mistral's new round would price the French startup at €20B, a 71% jump over last September's Series C, as it pitches European banks on sovereign AI.
Lilly's $2.3B Ajax bet just got its first clinical proof: AJ1-11095 hit 70% SVR35, more than double the historical ceiling for pre-treated MF.
Biopharma cut nearly 7,000 jobs in May, a 47% YoY surge: Takeda's 4,500 restructuring targets 200B yen in savings, BioNTech another €500M.
Amazon's $17.5B delayed-draw loan carries a Sept. 30 draw deadline and zero financial covenants, built to fund a $200B AI capex push.
Lilly's $25.27B deal spree in 2026 eclipses the combined M&A of every other top-12 pharma, and the obesity juggernaut isn't done yet.
J&J dropped $1 billion on a preclinical KRAS degrader platform at the exact moment Revolution Medicines proved the target is druggable.
Intesa Sanpaolo bid $35.3 billion for Monte Paschi at a 12.5% premium, blocking a BPM merger-of-equals offer that never named a price.
Roche drops $700M upfront and up to $3B total for Nurix's bexobrutideg, a BTK degrader headed into a phase 3 showdown with Lilly's Jaypirca.
S&P held its profitability screen, costing SpaceX $14B in passive fund demand and putting OpenAI and Anthropic on the same minimum one-year clock.
Google rents 110,000 Nvidia GPUs from SpaceX at $920M a month, bridging a Gemini Enterprise demand surge that a $190B capex plan can't keep pace with.
Nubank hired a former Visa North America CFO, Revolut downgraded its CTO title, and Adyen's CFO quit for a job outside fintech, all in one week.
Alphabet priced an $84.75B equity sale on June 2, the largest stock offering in recorded history, with Berkshire Hathaway in for $10B.
Alphabet's $80B equity raise, anchored by Berkshire's $10B, signals the moment AI capex outpaces Big Tech's collective ability to self-fund.
Amazon hit £15 billion of a £40 billion UK pledge in year one, ahead of pace, while embedding a new payment into Prime's billing chain.
Lilly's $75M upfront bet on Hanmi's once-monthly GLP-2 could reach $1.26B if sonefpeglutide survives FDA, and its main rival already stumbled.
Lilly's $3.2B upfront bet on Kelonia just got its first real validation: 18 of 18 myeloma patients hit MRD-negative status at one month.
Anthropic's Series H puts its valuation at $965 billion, a 154% step-up from February, with an investor list that reads like an IPO roadshow roster.
Pfizer's $650M entry into China's early oncology machine mirrors BMS-Hengrui by two weeks, and neither buyer has Phase 1 data to show for it.
Groq licensed its chip IP to Nvidia for $20B and lost its founding team. Now the remnant is raising $650M for a neocloud second act.
IBM bet $5B and 20,000 engineers on enterprises paying for secured open source, with Goldman Sachs, JPMorganChase, and nine other banks already in.
Goldman's chief of staff is out in June, making two management committee exits this year — the second shadowed by the Epstein fallout.
Charter denies any sensitive data left its systems, but ShinyHunters claims 40 million records stolen and demands payment by May 27.
Uber's board is weighing whether to top €38 a share for Delivery Hero as DoorDash circles. A key shareholder has already said no twice.
Mastercard paid half of Brazil's $997M Will Bank tab and wants processors to cover the rest. Cielo says acquirers never owned the risk.
Makary's 13 months at the FDA ended May 12 over a flavored-vape standoff, with food deputy Kyle Diamantas now acting commissioner.
CVC and GBL bid €10.7B to take Recordati private, but a 13% premium to the March price is a thin ask when you already control the register.
Europe's flagship crypto framework is barely two years old, and Brussels is already asking if it can survive dollar stablecoins' global grip.
Eli Lilly paid up to $202M for a preclinical biotech with zero disclosed programs: the platform bet driving its $21B 2026 buying spree.
Immunovant paid $39M in exit costs on batoclimab after two phase 3 TED trial failures, while next-gen IMVT-1402 RA data lifted shares 20%.
Acceleron veterans bet Westlake BioPartners' $30M on ORJ-001, a first-in-class IPF peptide with Phase 1 data in hand and Phase 2 next.
Commure raised $70M at a $7B valuation, with General Catalyst doubling down on AI that automates 85% of hospital billing without human hands.
Regeneron pays $125M upfront in a $2.3B Parabilis collaboration to build antibody-helicon conjugates, a drug class that doesn't exist yet.
Boston Scientific paid $1.5B for 34% of MiRus and locked in a $3B option for its SIEGEL TAVR system, one year after scrapping its own valve program.
Andrea Pfeifer ends her run at AC Immune, sending the company into its first-ever CEO search.
Left Lane Capital's $34M Series B in equipifi targets the 49% of credit union members already routing BNPL through outside providers.
NYC Mayor Mamdani is asking regulators to kill Western Union's $500M Intermex buy, citing fee hikes that would hit immigrant families hardest.
The FCC cleared EchoStar spectrum for AT&T and Starlink, leaving rural carriers to fight for secondary deals that may never materialize.
Alphabet's Isomorphic Labs closed a $2.1B Series B, the second biggest biotech fundraise ever, with no pipeline molecule disclosed.
FinCEN's 7 April NPRM rewrites 25 years of AML rules. Buried in the fact sheet: AI use will weigh on how the Director sets fines.
BMS commits $950M up front for a 13-asset onco-immune pipeline with Hengrui that could balloon to $15.2B if every milestone clears.
CSL's $5B write-down paired with a 4% guidance cut drove shares to a nine-year low; investors aren't convinced the cleanup is done.
Odyssey Therapeutics priced a $304M IPO at $18 per share, at the top of its range, with $135M earmarked for a RIPK2 inhibitor in ulcerative colitis.
Lilly's $4.5B Indiana bet includes the company's first genetic medicine plant and what could become the largest API site in U.S. history.
Roche is dropping $750M upfront for PathAI, with another $300M in milestones riding on a pathology software platform it wants to take global.
Angelini Pharma dropped $4.1B on Catalyst and its trio of FDA-approved rare neurology treatments; the per-share premium wasn't disclosed.
GSK paid up to $1B for SiranBio's Phase 1 siRNA asset targeting ALK7, doubling down on cardiometabolic bets while GLP-1 rivals pile up.
Lilly's $4.5B Lebanon push brings its U.S. decade commitment over $50B, with a tirzepatide API plant poised to be the country's largest.
The crypto exchange is paying $4.2B for capital markets plumbing: a transfer agent processing $500B annually for 20 million shareholders.
Madrigal's $1B bet on Arrowhead's ARO-PNPLA3 targets a PNPLA3 mutation affecting 30% of MASH patients that Rezdiffra doesn't cover.
Amgen drops another $300M into its Puerto Rico biologics site, bringing Juncos to nearly $1B total and U.S. manufacturing pledges close to $2B.
GameStop offered $55.5B for eBay at $125 a share, a 46% premium, but CNBC's math found a $16 billion gap Ryan Cohen couldn't explain.
Swiss biotech Windward Bio raised $165M to advance a China-derived drug into late-stage testing. What investors get from this bet is the real question.
Ken Song has done it again.
UCB bought Candid Therapeutics for $2 billion upfront, plus up to $200 million in development milestones, cutting off a planned reverse merger with…
Novartis has committed $23 billion to build seven U.S. facilities, and the final piece just landed in Morrisville, North Carolina: a 56,200-square-foot…
Sun Pharma paid $11.75 billion for Organon, the largest biopharma acquisition of 2026 and the biggest deal any Indian drugmaker has ever announced.
BeOne Medicines is paying $20 million upfront to reserve an exclusive option on HH160, a preclinical trispecific antibody from Beijing-based Huahui Health.
OppFi paid $130 million for BNCCORP and its BNC National Bank subsidiary, a cash-and-stock deal that values the Glendale, Arizona lender at 1.2 times its…
Adyen paid €750 million ($876 million) in cash to buy Talon.
Chiesi paid roughly $1.9 billion to buy KalVista Pharmaceuticals, an Italian pharma adding a commercial-stage biotech to its portfolio.
AbbVie has secured an exclusive right to buy Kestrel Therapeutics for up to $1.45 billion, with the biotech required to hit unspecified development and…
Sun Pharma paid $11.75 billion, or $14 a share in cash, to buy Organon in a deal that positions the India-based generics maker among the world's biosimilar…
Eli Lilly paid up to $2.3 billion for Ajax Therapeutics on April 27, adding a Phase 1 myelofibrosis asset to a deal streak that's included Verve ($1B…
Eli Lilly bought an in vivo CAR-T biotech, terms undisclosed.
Google put $10 billion into Anthropic on Friday at a $350 billion valuation, with another $30 billion committed contingent on performance milestones.
Thermo Fisher paid $9 billion for Clario and got $30 million back in Q1.
Kailera Therapeutics raised $625 million in a record IPO for an obesity biotech.
Regeneron signed the White House's most-favored-nation drug pricing deal Thursday, becoming the 17th and final company to do so — closing out a sweep that…
AbbVie has allocated $1.4 billion for a manufacturing campus in Durham, North Carolina, its first in the state, drawn from the company's $100 billion US…
Merck paid $1 billion to Google Cloud for access to its agentic AI platform, and the commercial team gets there first.
Amneal paid $1.1 billion to buy Kashiv BioSciences: $750 million upfront in cash and equity at close, plus up to $350 million tied to pipeline milestones.
Forager Capital Management offered $1 billion for Atlanta-based Repay Holdings at $4.80 a share, a 75% premium to the stock's 30-day volume-weighted average…
Apollo Funds paid $1.25B for a 13% minority stake in McKesson's Medical/Surgical Solutions division, valuing MMS at roughly $13 billion.
Venrock put $20 million into Kelonia Therapeutics.
Lilly paid an undisclosed sum upfront for Kelonia Therapeutics on Monday, placing a large bet on in vivo CAR-T as its next platform priority.
Kailera Therapeutics raised $625 million Friday in a record-setting biotech IPO on the Nasdaq.
Kraken paid up to $550 million for Bitnomial, a derivatives firm, in a deal that closes by June.
UCB paid up to $650m upfront, with up to $500m in future milestones, to buy Neurona Therapeutics in a deal valued at up to $1.15bn.
Fifth Third bought Comerica in February, folding in about $294 billion in assets and roughly 500,000 retail customers.
Kailera Therapeutics priced just under 40 million shares at $16 apiece Friday, pulling in $625 million on its Nasdaq debut under KLRA.
Revolution Medicines had a rumored $30 billion buyout offer on the table in January.
Kailera Therapeutics priced its IPO at $625m, or $16 a share, on April 16 — at the top of its S-1 range and one of the largest biotech public offerings…
Kailera Therapeutics priced its IPO at $16 a share Friday, raising $625 million, the largest biotech public offering in recent memory, topping Moderna's…
Daiichi Sankyo will sell its consumer health subsidiary to Suntory Holdings for 246.5 billion yen, about $1.55 billion, paid in tranches over three years.
Nir Zuk, the Israeli billionaire who founded Palo Alto Networks, filed a Federal Reserve application Wednesday to acquire voting shares of DMG Bancshares…
Biopharma committed $22 billion to obesity and diabetes licensing deals in Q1 2026, clearing last year's full-year total of $20.3 billion with three…
Aligos Therapeutics sold the Greater China rights to pevifoscorvir sodium to Fujian-based Amoytop for up to $445 million: $25 million upfront and $420…
Revolution Medicines is raising $2 billion in a stock offering priced at $142 per share, up from the $1 billion it announced Monday, hours after reporting…
Revolution Medicines just priced a public equity raise, the largest single biotech offering since the Covid-19 pandemic.
Daiichi Sankyo sold its consumer health unit to Suntory Holdings for 246.5 billion yen, roughly $1.55 billion, in a staged transfer that kicks off this June…
Biogen paid $5.6B for Apellis, and a new SEC filing confirmed the deal details CEO Chris Viehbacher has been engineering: a company that doesn't grow on…
Bain Capital put $300 million into Beeline Medicines at launch, licensing five autoimmune programs from Bristol Myers Squibb to build its next specialty…
Alamar Biosciences wants $159 million from public markets, pricing 9.4 million shares at $15 to $17 apiece for a Nasdaq listing under "ALMR.
Click Therapeutics raised Series D funding, then cut more than a quarter of its workforce shortly after.
AbbVie bought ex-China rights to two NaV1.8 sodium channel pain inhibitors from Beijing-based Haisco Pharmaceutical for up to $745 million.
Kailera filed for a $528.5 million Nasdaq IPO, pricing 33.33 million shares at $14 to $16 each.
Regeneron put $40 million on the table Sunday to partner with Telix Pharmaceuticals, the Australian biotech with one of the more active radiopharmaceutical…
Julius Baer has been counting losses for two years.
Blackstone filed confidential IPO paperwork with U.S. regulators to raise $2 billion for a dedicated acquisition vehicle targeting data centers, Bloomberg…
Novo Nordisk is losing a key obesity figure.
Shionogi has been awarded a $119 million contract from BARDA for Fetroja, a direct government commitment to the drugmaker's drug.
Jeito Capital closed Jeito II at more than €1bn, lifting the firm's total AUM to €1.6bn.
BARDA paid $482m to get Fetroja made on US soil.
Roche is paying $20 million upfront for access to two degrader-antibody conjugate (DAC) programs from C4 Therapeutics, with more than $1 billion in…
Polygon Labs seeks $50M-$100M in equity to build its Open Money Stack stablecoin platform, a bet on payments as its native token shed 90% of its value.
PhRMA leader Steve Ubl plans to step down at a pivotal moment for pharma's most powerful DC trade group, Endpoints News reports.
Gilead bought Arcellx, Ouro, and Tubulis for $14.77B in under ten weeks. CFO says further big deals are unlikely this year, but the door stays open.
KreditBee joins India's unicorn club as investors bet on the country's underserved lending market.
Merck cut its Terns offer from $7.7B to $6.7B after Phase 1 leukemia data disappointed. The rival bidder walked entirely.
Whoop's $575M Series G tops a Q1 health tech funding wave built on AI clinical workflow bets, with no post-money valuation disclosed yet.
Eli Lilly acquires into the orexin drug class, betting the maturing CNS mechanism follows the same multi-indication arc as GLP-1.
Digital health hit $4B in Q1 2026, up $1B year-over-year, but 12 mega-deals claimed 59% of all capital as total deal count fell to 110.
Apnimed secured up to $150M from HCRx to launch AD109, with only $50M unconditional and the rest tied to FDA approval and a sales milestone.
Gilead's $3.15B upfront buy of Tubulis adds a 59%-ORR NaPi2b ADC to its pipeline — its third acquisition of 2026, totaling over $12B spent.
Lilly is paying $7.8B for Centessa — $38/share plus a $9 CVR — to grab cleminorexton, a Phase IIa orexin agonist for narcolepsy.
Takeda filed a WARN notice to cut 634 US jobs, with 247 hitting its Cambridge headquarters — the largest concentration in the restructuring.
Syneron Bio raised a $150M Series B for peptide development. GLP-1s proved the format can print billions. The program list is still a mystery.
Neurocrine is paying $2.9B at ~15x trailing revenue for Soleno's Vykat XR, the only approved drug for Prader-Willi hunger, in its biggest-ever deal.
Anthropic acquires six-person AI biotech Coefficient Bio for $400M in stock — $66M per employee for a company founded in 2025 with no public product.
Takeda returns frontotemporal dementia drug DNL593 to Denali after 8 years and $150M, citing strategy—not safety—days after Denali's FDA approval win.
Anthropic is paying ~$400M for Coefficient Bio, a sub-10-person stealth startup. The price signals how expensive life sciences AI talent has become.
Stipple Bio launches with $100M to identify precise targets on cancer proteins, betting the ADC industry's real problem is aim, not ammo.
Neurocrine pays $53/share in cash for Soleno Therapeutics, acquiring Vykat XR, a profitable approved treatment for Prader-Willi syndrome.
Gilead cuts 51 Foster City jobs effective May 29, one year after the same HQ shed 149. The backdrop: ~$10B in acquisitions closed since February.
Syneron Bio raises $150M Series B, bringing total funding to $250M in four months, backed by AstraZeneca and Abu Dhabi sovereign wealth.
OpenEvidence acquires Tandem to add AI-driven prior authorization to its doctor-facing platform, threatening standalone PA automation vendors.
Eli Lilly paid $115M upfront for an AI collaboration with Insilico Medicine worth up to $2.75B, with milestone math that heavily favors Lilly.
Two pharma giants closed megadeals in March while Blackstone raised a new fund — more dry powder chasing the same targets means multiples only go one way.
Biogen acquires Apellis for $5.6B at a near 140% premium, adding Syfovre and Empaveli to offset a fading MS franchise ahead of pharma's patent cliff.